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KMID : 1031120110010020071
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Journal of Epilepsy Research
2011 Volume.1 No. 2 p.71 ~ p.73
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Staged Total Callosotomy for Lennox-Gastaut Syndrome: A Case Report
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Lee Eun-Hye
Yum Mi-Sun
Hong Seok-Ho
Lee Jeong-Kyo
You Su-Jeong
Ko Tae-Sung
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Abstract
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We report a case with Lennox-Gastaut syndrome (LGS) who underwent staged total callosotomy with a favorable outcome. A 6-year-old boy began having myoclonic seizures at the age of 8 months and was diagnosed with LGS when he was 27 months old. Various antiepileptic drugs and a ketogenic diet failed to control his multiple types of seizures. At the age of 36 months, he underwent corpus callosotomy and achieved an immediate, post-operative seizure free state. However, 3 months later, various seizures relapsed and were refractory to additional vagus nerve stimulation. Remaining callosal fibers in the splenium noted on post-operative diffusion tensor imaging made us to perform a second operation, total callosotomy. The patient finally achieved a seizure-free state with electroencephalography (EEG) normalization noted after the staged total callosotomy.
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KEYWORD
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Lennox-Gastaut syndrome, Callosotomy
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